Andrea Fleig Selected Research

Neoplasms (Cancer)

1/2021	Role of TRPM7 kinase in cancer.
1/2018	The TRPM7 kinase limits receptor-induced calcium release by regulating heterotrimeric G-proteins.
1/2017	Inhibition of TRPM7 suppresses cell proliferation of colon adenocarcinoma in vitro and induces hypomagnesemia in vivo without affecting azoxymethane-induced early colon cancer in mice.
1/2014	TRPM7.
8/2013	TRPM7 is regulated by halides through its kinase domain.
11/2011	Waixenicin A inhibits cell proliferation through magnesium-dependent block of transient receptor potential melastatin 7 (TRPM7) channels.

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Andrea Fleig Research Topics

Disease

6	Neoplasms (Cancer) 01/2021 - 11/2011
2	Brain Injuries (Brain Injury) 01/2021 - 12/2020
2	Brain Ischemia (Cerebral Ischemia) 12/2020 - 01/2018
2	Hyperglycemia 01/2018 - 06/2010
2	Colonic Neoplasms (Colon Cancer) 11/2017 - 01/2017
2	Inflammation (Inflammations) 05/2013 - 07/2008
1	Pathologic Processes 01/2021
1	Glioblastoma (Glioblastoma Multiforme) 12/2020
1	Central Nervous System Diseases (CNS Diseases) 12/2020
1	Stroke (Strokes) 12/2020
1	Atrophy 11/2020
1	Insulinoma 10/2017
1	Colorectal Neoplasms (Colorectal Cancer) 01/2017
1	Carcinogenesis 01/2017
1	Aberrant Crypt Foci 01/2017
1	Adenocarcinoma 01/2017
1	Hypersensitivity (Allergy) 12/2014
1	Neuroblastoma 09/2014
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2014
1	Ischemia 01/2014
1	Breast Neoplasms (Breast Cancer) 08/2013
1	Asthma (Bronchial Asthma) 05/2013
1	Parkinson Disease (Parkinson's Disease) 01/2013
1	Type 2 Diabetes Mellitus (MODY) 06/2010
1	Insulin Resistance 06/2010
1	Colitis 07/2008
1	Infections 07/2008
1	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2008
1	Multiple Sclerosis 01/2008
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2008
1	Autoimmune Diseases (Autoimmune Disease) 01/2008

Drug/Important Bio-Agent (IBA)

5	waixenicin AIBA 01/2021 - 11/2011
4	MagnesiumIBA 01/2018 - 01/2014
3	CationsIBA 01/2021 - 09/2014
3	Proteins (Proteins, Gene)FDA Link 12/2020 - 06/2010
2	Glucose (Dextrose)FDA LinkGeneric 01/2018 - 06/2010
2	CalciumIBA 01/2018 - 05/2013
2	AzoxymethaneIBA 11/2017 - 01/2017
2	Reactive Oxygen Species (Oxygen Radicals)IBA 05/2013 - 07/2008
1	Phosphotransferases (Kinase)IBA 01/2021
1	CalcineurinIBA 01/2021
1	Calcium-Calmodulin-Dependent Protein KinasesIBA 01/2021
1	Pharmaceutical PreparationsIBA 12/2020
1	(R)- N- (benzimidazol- 2- yl)- 1,2,3,4- tetrahydro- 1- naphthylamineIBA 11/2020
1	scalaradialIBA 10/2017
1	Small Interfering RNA (siRNA)IBA 09/2014
1	IodidesIBA 08/2013
1	ChloridesIBA 08/2013
1	sodium-iodide symporter (sodium iodide symporter)IBA 08/2013
1	AllergensIBA 05/2013
1	Aluminum Hydroxide (Algeldrate)FDA Link 05/2013
1	AntibodiesIBA 05/2013
1	Ion Channels (Ion Channel)IBA 05/2013
1	Transient Receptor Potential ChannelsIBA 05/2013
1	OvalbuminIBA 05/2013
1	CytokinesIBA 05/2013
1	Blood Glucose (Blood Sugar)IBA 06/2010
1	Arginine (L-Arginine)FDA Link 06/2010
1	ChemokinesIBA 07/2008
1	Dextran SulfateIBA 07/2008
1	Kv1.3 Potassium ChannelIBA 01/2008

Therapy/Procedure

1	Therapeutics 11/2011